We aim to shape the gut microbiome through targeted dietary interventions, leveraging artificial intelligence and genome-scale metabolic modeling. Our goal is to illuminate the functional dark matter of gut bacteria and unravel how diet is biotransformed in the human gut, generating a vast and largely unexplored chemical space.
Rather than relying on broad dietary patterns that are difficult to sustain long-term, we seek to develop precise molecular interventions that actively shape the microbiome to promote health. Additionally, we are exploring ways to enhance the nutritional value of foods by modulating their natural microbiome.
Our efforts are supported by two European initiatives—the
NutriImmune
and
FoodGuard
consortia—driving innovation at the intersection of microbiome science, AI, and nutrition.